Daylite, customer relationship software
We’ve been searching for a good customer relationship application for a long time. Daylite is a Mac-only application that plays nice with Apple Mail, and it rocks. 

MYOB
We  hate that Intuit’s Mac version of QuickBooks sucks so badly. Enter MYOB.

Modo and Lightwave (3D applications)
Product demos, visualizations, animations, and more. We used Lightwave for effects shots with Couch Cases. It’s great. Modo is even cooler in some ways, but most importantly they play well together.

Adobe CS4 Master Collection
Everything we do uses some piece of software in this collection. It’s expensive, but worth every penny.

WordPress (obviously!)
You’re reading why.

ModX CMS system
The only CMS we’ve found that gives the freedom to design like things should be designed- using web standards and CSS.

Firefox
Hands down the best browser on the planet, especially with its plugins.